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BACTERIAL INFECTIONS
Bacteria are the oldest and most abundant organisms on Earth.
Bacterial cells are smaller than the human red blood cell. Unlike human and
animal cells, they lack a nucleus. Like plant cells, bacteria are surrounded by
a carbohydrate cell wall. Bacterial species are responsible for many of the
world's infectious diseases. Unlike viruses, which also cause infections,
bacterial infections can be treated more effectively with antibiotics that kill
them or disable growth or reproduction.
Bacteria are both helpful hosts and harmful sources of disease. In
the large intestine, native bacteria aid in digestion and prevent the build-up
of other toxic bacterial species.
What Are Bacteria?
You would be amazed at the hosts of critters out there waiting to
take up residence in your body. There's everything from tapeworms that are yards
long to tiny protein fragments (prions) that can multiply in your brain and give
you Creutzfeldt-Jakob disease, the human version of mad cow disease. They're all
lurking just out of reach of your senses. We will discuss here only one category
of germs - bacteria.
Known to scientists as procaryotes, bacteria are the largest class of
creatures on earth, even larger than beetles. They are very simple organisms --
single cells with no nucleus. Nevertheless, they eat, are capable of reproducing
themselves, and have a membrane or shell that separates their insides from the
outside world.
Bacteria, the most familiar of infecting agents, cause 90 percent of
hospitalized infections in developing countries, although they contend with
viruses for being the most diversified. Bacteria cause most of the serious,
acute infections we get and are the first group of germs to yield to chemical
cures, which is to say, antibiotics. From bacteria we get urinary and kidney
infections, strep throats, pink eye, boils, typhoid, cholera, tetanus, gangrene,
diphtheria, whooping cough, anthrax, Lyme disease and most of the serious cases
of dysentery, meningitis and pneumonia. But they can't take credit for viral
hepatitis, colds, influenza, rabies, AIDS, giardiasis, malaria, worms, athlete's
foot, hantavirus, kuru, bovine spongiform encephalopathy, lymphocytic
choriomeningitis, Ebola virus or bread mold. Because it is so important, we'll
also call tuberculosis (TB) a bacterium, even if that classification is not
quite accurate.
For the most part, bacteria are the smallest free-living organisms in
nature, having all the genetic material necessary to live independently. This is
not to say that many of them don't enjoy the parasitic life, but as a class they
are complete life forms unto themselves. Smaller living organisms such as
viruses are obligate parasites, unable to survive outside another living system,
such as yours, for example.
How bad are bacteria?
Bacterial infections fill the space between pimples and plague.
Recently doctors have discovered bacterial infections can even cause stomach
ulcers. They also cause toxic shock syndrome and the recently publicized E.
coli infections children get from contaminated public swimming pools or
hamburger meat. Bacteria are responsible for the bubonic plagues that ravaged
Since Alexander Fleming discovered penicillin in 1928, bacteria have
encountered a new enemy, and have responded very ingeniously. Within 50 years,
nearly all disease-causing bacteria have developed resistance to at least one
antibiotic. They have even learned how to pass their resistance on to their
relatives. But the most frightening news is that some bacteria have developed
resistance to EVERY known antibiotic. Much of this resistance has come from
improper use of antibiotics, which is the main reason you will never be able to
buy them over the counter, at least in this country. Incomplete doses kill all
but the hardiest germs, which are then able to develop even stronger resistance
through mutation and "natural selection." The lessons here are "Finish your
prescription. Kill them all, or they'll come back to get you, and don't take
antibiotics for illnesses caused by viruses." Given the tens of millions of
dollars and the years of processing required to get a single new drug on the
market, bacteria have a clear advantage when it comes to
efficiency.
TB
is a classic example of selective development of resistance. It used to be
universally susceptible to INH (isonicotinic acid hydrazide), a cheap, safe
treatment that spread around the world. Inadequate dosing was the rule rather
than the exception, especially since it takes months, rather than days, to
eradicate TB in a patient. Now, TB can be resistant not only to INH, but also to
many more expensive and more toxic drugs. Some TB strains are resistant to every
drug. Now that AIDS has released TB from the constraints of our natural
immunity, TB is increasing by as much as twenty-fold in African countries
heavily stricken with AIDS. TB throughout history has been the number one
killer.
TB
isn't exactly a bacterium. TB is called a mycobacterium because it is very much
like a bacterium, but "myco" because it has some properties that resemble the
next higher category, fungi. Leprosy, now known as Hansen's disease, is also
caused by a mycobacterium.
Is It an Allergy or
Sinusitis?
According to a survey of doctors and patients, 42 percent of those
surveyed said they suffered through at least one sinus infection in the past 12
months, a jump of 9 percent from the previous year. And 39 percent of them said
their sinusitis started with an allergy, while 28 percent said the infection
began with a cold.
The survey also shows sinus problems wreak havoc with daily life.
More than half of those questioned say they lost sleep at least twice during the
allergy season last year, and 42 percent missed anywhere from one to seven or
more days of work or school because of the nasty and bothersome
infection.
Severe allergy season a factor
This year's unusually warm winter is not going to make it any easier
on sinuses, according to the
"This year's warm temperate winter means we are going to see an earlier and more severe allergy season this spring. And with a more severe allergy season, we're going to see a jump in the number of sinus infections."
Blame swollen sinus passages caused by an allergy or a cold for sinusitis." Those warm, wet passages are a playground for bacteria. "An inflamed swollen sinus passage leads to blockage of the sinus opening and a backing up of nasal and sinus mucous."
Sinusitis is one of the most commonly
reported diseases in the United States, affecting an estimated 37 million people
and accounting for more than 11.5 million visits to the doctor each year.
How to tell if you have sinusitis
"The problem is, that most people can't tell the difference between allergies or a cold and sinusitis."
A couple variables differentiate allergies or colds from sinusitis. "People need to understand that a head cold and allergies can prime the sinuses, making them inviting to bacteria. Sinusitis generally lasts 10 to 28 days and usually follows a cold or allergies. So, if you've got pain in the forehead or the face, accompanied by coughing, fever and nasal congestion lasting more that two weeks, you need to go and see the doctor."
The second variable is the nature of the mucus that develops.
"Allergies usually involve itching and clear, watery nasal discharge. But if
you're getting excessive thick, sticky yellow-green mucous or mucous that tastes
bad, you need to seek the advice of a doctor."
The cure for sinusitis?
"Antibiotics are the only things that work on bacterial sinusitis.
For More Information:
Please consult
your attending physician on your next
visit.
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