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BLEEDING TIME
Definition
Bleeding time is a crude test of hemostasis (the arrest or stopping
of bleeding). It indicates how well platelets interact with blood vessel walls
to form blood clots.
Purpose
Bleeding time is used most often to detect qualitative defects of
platelets, such as Von Willebrand's disease. The test helps identify people who
have defects in their platelet function. This is the ability of blood to clot
following a wound or trauma. Normally, platelets interact with the walls of
blood vessels to cause a blood clot. There are many factors in the clotting
mechanism, and they are initiated by platelets. The bleeding time test is
usually used on patients who have a history of prolonged bleeding after cuts, or
who have a family history of bleeding disorders. Also, the bleeding time test is
sometimes performed as a preoperative test to determine a patient's likely
bleeding response during and after surgery. However, in patients with no history
of bleeding problems, or who are not taking anti-inflammatory drugs, the
bleeding time test is not usually necessary.
Precautions
Before administering the test, patients should be questioned about
what medications they may be taking. Some medications will adversely affect the
results of the bleeding time test. These medications include anticoagulants,
diuretics, anticancer drugs, sulfonamides, thiazide,
aspirin and aspirin-containing preparations, and nonsteroidal
anti-inflammatory drugs. The test may also be affected by anemia (a
deficiency in red blood cells). Since the taking of aspirin or related drugs are
the most common cause of prolonged bleeding time, no aspirin should be taken two
weeks prior to the test.
Description
There are four methods to perform the bleeding test. The Ivy method
is the traditional format for this test. In the Ivy method, a blood pressure
cuff is placed on the upper arm and inflated to 40 mM Hg. A lancet or scalpel
blade is used to make a stab wound on the underside of the forearm. An
automatic, spring-loaded blade device is most commonly used to make a
standard-sized cut. The area stabbed is selected so that no superficial or
visible veins are cut. These veins, because of their size, may have longer
bleeding times, especially in people with bleeding defects. The time from when
the stab wound is made until all bleeding has stopped is measured and is called
the bleeding time. Every 30 seconds, filter paper or a paper towel is used to
draw off the blood. The test is finished when bleeding has stopped
completely.
The three other methods of performing the bleeding test are the
template, modified template, and Duke methods. The template and modified
template methods are variations of the Ivy method. A blood pressure cuff is used
and the skin on the forearm prepared as in the Ivy method. A template is placed
over the area to be stabbed and two incisions are made in the forearm using the
template as a location guide. The main difference between the template and the
modified method is the length of the cut made.
For the Duke method, a nick is made in an ear lobe or a fingertip is
pricked to cause bleeding. As in the Ivy method, the test is timed from the
start of bleeding until bleeding is completely stopped. The disadvantage to the
Duke method is that the pressure on the blood veins in the stab area is not
constant and the results achieved are less reliable. The advantage to the Duke
method is that no scar remains after the test. The other methods may result in a
tiny, hairline scar where the wound was made. However, this is largely a
cosmetic concern.
Preparation
There is no special preparation required of the patient for this
test. The area to be stabbed should be wiped clean with an alcohol pad. The
alcohol should be left on the skin long enough for it to kill bacteria at the
wound site. The alcohol must be removed before stabbing the arm because alcohol
will adversely affect the tests results by inhibiting
clotting.
Aftercare
If
a prolonged bleeding time is caused by unknown factors or diseases, further
testing is required to identify the exact cause of the bleeding
problem.
Normal results
A
normal bleeding time for the Ivy method is less than five minutes from the time
of the stab until all bleeding from the wound stops. Some texts extend the
normal range to eight minutes. Normal values for the template method range up to
eight minutes, while for the modified template methods, up to 10 minutes is
considered normal. Normal for the Duke method is three
minutes.
Abnormal results
A
bleeding time that is longer than normal is an abnormal result. The test should
be stopped if the patient hasn't stopped bleeding by 20-30 minutes. Bleeding
time is longer when the normal function of platelets is impaired, or there are a
lower-than-normal number of platelets in the blood.
A
longer-than-normal bleeding time can indicate that one of several defects in
hemostasis is present, including severe thrombocytopenia, platelet
dysfunction, vascular defects, Von Willebrand's disease, or other
abnormalities.
Key Terms
Hemostasis
The stopping of bleeding or blood flow
through a blood vessel or organ.
For
More
Information:
Please consult your
physician on your next
visit.
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